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While existing GLP-1 medications have shown greater weight loss than Eli Lillys oral medication, the oral option targets both weight loss and type 2 diabetes in patients

The dual hit hypothesis of schizophrenia: evidence from animal models

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The activation of PLC results in the release of inositol-1,4,5-trisphosphate (IP 3 ) from membrane associated phosphatidylinositol-4,5-bisphosphate (PIP 2 ), which then binds to specific IP 3 receptors in the endoplasmic reticulum/sarcoplasmic reticulum (ER/SR) resulting in the release of intracellular stores of Ca 2+