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AMPK may also mediate other effects of estrogens, e.g

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Consequently, analyses of gender, weight, outcomes, and TTO are necessarily restricted to the subset of cases with available information

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Of note, many of these cases exhibit CSF oligoclonal bands, Gd-enhancing lesions on MRI and clinical response to immunosuppressionall features very typical of MSindicating that secondary immune responses to a primary trigger can play a significant role in the final clinical phenotype