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The pathogenesis of age-related nuclear cataract is largely attributed to the chronic exposure of the lens to molecular oxygen, resulting in oxidative damage to proteins in the lens nucleus, protein aggregation, light scattering, and ultimately loss of lens transparency [37,38,39,40,41,42]

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Hessler DM, Fisher L, Polonsky WH et al (2017) Diabetes distress is linked with worsening diabetes management over time in adults with type 1 diabetes