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Every patient in our healthcare system will be approached to participate in research. Even though a 1993 law requires all medical research funded by the National Institutes of Health (NIH) to adequately include minorities, a study by the University of California, San Francisco, of more than 10,000 cancer clinical trials funded by NIH since 1993 found that less than 2 percent succeeded in enrolling enough minority participants

The progressive loss of nephrons reduces renal 1-hydroxylase activity, limiting the production of active 1,25-dihydroxyvitamin D (1,25(OH)D), whereas urinary loss of vitamin D-binding protein (VDBP) due to proteinuria further exacerbates 25(OH)D deficiency (3)

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doi: 10.1186/s13048-020-00738-0 76 DonabelaFCMeolaJPadovanCCde PazCCNavarroPA

Kondo S, Kubota S, Mukudai Y, Nishida T, Yoshihama Y, Shirota T, et al