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Key findings included: Nearly 16% non-placebo-adjusted weight loss on 2.4 mg weekly berobenatide No weight-loss plateau observed through 32 weeks of extension treatment Successful transition from weekly induction to monthly maintenance dosing Favorable gastrointestinal tolerability despite rapid dose escalation These results provide proof-of-concept for monthly GLP-1 therapy while maintaining competitive efficacy

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10.1038/cddis.2011.117 [DOI] [PMC free article] [PubMed] [Google Scholar] 81.Wang S-J, Wu W-M, Yang F-L, Hsu G-SW, Huang C-Y

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