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A randomized controlled trial from 2021 found that oral GSH supplementation improved insulin sensitivity in obese subjects with and without T2DM, although it didnt alter other markers of oxidative stress

These medications can lead to a significant and clinically meaningful reduction in body weight when used in conjunction with lifestyle changes

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Additionally, a multi-country study found substantial demand for GLP-1 medications among people without medical indications, highlighting the evolving landscape of body image and obesity treatment (Jensen et al., 2025)