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[2] [3] [4] In addition to its efficacy in epilepsy and migraine prophylaxis, topiramate has also demonstrated neuroprotective effects against hypoxic-ischemic brain damage in both in vitro and animal models
One of the main identified targets is the nitric oxide (NO) pathway, where the peptide acts as a modulator of NO synthesis via NO synthase (NOS) enzymes
Using digital camera, tubules were transferred into ISSA- special software for morphometrical analysis (Vamstec, Zagreb, Croatia)
Mounjaro is available in pre-filled pens containing doses ranging from 2.5 mg to 15 mg, with treatment typically initiated at the lowest dose and gradually titrated upwards every 4 weeks to improve gastrointestinal tolerability
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