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To prevent the excessive antigen stimulation response, cancer cells suppress the T-cell activity by binding of PD-1 to ligand on cancer cells such as PDL-1

O-GlcNAcylation is mainly regulated by O-GlcNAc transferase and O-GlcNAcase, which are responsible for the addition or removal of O-GlcNAc

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However, potential AEs were also highlighted, emphasizing the need for careful evaluation in clinical practice to ensure proper usage

Effects of astragalus polysaccharides on immunologic function of erythrocyte in chickens infected with infectious bursa disease virus

Small intravenous human studies reported changes in sleep onset, sleep efficiency, total sleep time or daytime functioning in some settings