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There are several causes for upper GI bleeding, however the most common are peptic ulcer disease, variceal bleeding, and malignancy

However, in the case of selenoprotein messenger ribonucleic acid (mRNA), the 3untranslated region contains selenocysteine insertion sequence (SECIS) elements, which allow for the recognition of UGA as a selenium cysteine codon rather than a stop signal (21)