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Many other drugs decrease GSH levels because they induce oxidative stress, for example doxorubicin (adriamycin), antimalarial drugs, chloroquine (CQ), etoposide, opiates, ethanol [84] and antidepressants [85]

When oxidative stress is high, more GSH converts to GSSG

The available human pharmacokinetic study involved only 18 healthy adults receiving a single high dose

(PubMed) Bottom line: Glutathione injections are risky

[DOI] [PubMed] [Google Scholar] 164.Aksoy M., Kfrevioglu I

Journal of Nutritional Science and Vitaminology Reasons to Consider Glutathione Supplementation: Glutathione's anti-inflammatory properties can alleviate pain and discomfort associated with various conditions