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[15] [37] [38] In August 2025, the Food and Drug Administration (FDA) expanded the indication for semaglutide (as Wegovy) to include the treatment of noncirrhotic metabolic-associated steatohepatitis (MASH), formerly known as nonalcoholic steatohepatitis (NASH), with moderate to advanced liver fibrosis (consistent with stages F2 to F3 fibrosis) in adults

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Molecular size limits : GLP-1 is a peptide hormone with a molecular weight of about 3,300 daltons

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It protects cells from oxidative damage, supports detoxification pathways, and helps regulate immune functionall of which are essential for reproductive health