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However, despite evidence suggesting the positive effects of improved tumor vascularization, there is also a risk of enhanced cancer cell activity and accelerated tumor growth [42]

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Under resting conditions, the KEAP1 protein strictly represses the activity of NRF2

It noted that oral and intra-articular peptides showed distinct advantages in soft tissue regeneration, with intra-articular routes providing localized effects and oral routes offering systemic benefits

Lipid peroxidation markers such as malondialdehyde (MDA), 4-hydroxyl-2-nonenal (HNE), and isoprostane are used to evaluate oxidative damage