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GLP1 treatments such as semaglutide (Wegovy) Dualagonists such as tirzepatide (Mounjaro) Noninjectable options such as orlistat

Real-world clinical data shows an average weight reduction of just 1.1 to 1.5 percent during the first eight weeks of treatment

Semaglutide causes nausea in 44% of users, diarrhea in 30%, and vomiting in 24%

Rodent studies: Four preclinical studies investigated the effect of vitamin supplementation on ES-induced behavioral deficits

Propranolol may cause fatigue, but usually less sedation

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