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These are deemed essential fatty acids because they must be acquired through the diet, as the human body cannot synthesize them independently

However, conditions affecting the gastrointestinal tractincluding pernicious anaemia, Crohn's disease, coeliac disease, or gastric surgerycan significantly impair absorption, necessitating alternative supplementation routes such as intramuscular hydroxocobalamin injections, which deliver B12 directly into the bloodstream

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Additionally, it can be beneficial for individuals suffering from chronic fatigue syndrome, fibromyalgia, and other chronic illnesses