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The rash can be caused by an allergic reaction to tirzepatide or to ingredients in the injection (like preservatives), or as a localized response to the needle or injection technique
Semaglutide, the generic name for the drug, was tested in clinical trials from 2016 to 2017, prior to approval by the FDA to treat type 2 diabetes in adults
The medication comes in a pre-filled pen that makes self-injection straightforward
For patients who have had a cardiovascular event and heart failure, SGLT2 inhibitors are recommended as first-line treatment, GLP-1 RAs or metformin as second-line treatment, and DPP4 inhibitors, acarbose, or insulin as third-line treatment [5]
STAT News noted that the new deal stems from pricing negotiations rather than a full legislative overhaul
