glutathione lung cancer platinum resistance A cisplatin-based platinum(IV) prodrug containing a s-transferase inhibitor to reverse cisplatin-resistance in non-small cell Frontiers lung cancer glutathione Anti-human activities

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However, CHAC1 loss promoted a significant reduction in the functionality of these Fe-S proteins under cystine deprivation (Supplementary Fig

Our subsequent studies in human endothelial cells showed that the homocysteine metabolite, S-adenosylhomocysteine, a potent inhibitor of many methyltransferases, decreased tRNA Sec methylation to suppress GPx1 expression and activity [69]