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This protection is likely due to increased growth of new neurons in the hippocampus, improved signaling of brain-derived neurotrophic factor (BDNF), better synaptic function, and reduced brain inflammation (Nichol et al., 2008)

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BUT there was a really nice comparison done of weight regain in behavioral interventions vs

The same energy deficit in obese people, may, in turn, result in a neutral or positive impact on the levels of the hormone

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