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doi: 10.3389/fphar.2022.977385 Received 24 June 2022 Accepted 01 September 2022 Published 27 September 2022 Volume 13 - 2022 Edited by Sai Wang Seto, Hong Kong Polytechnic University, Hong Kong SAR, China Reviewed by Dominic Del Re, The State University of New Jersey, United States Karen R