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Some users experience tingling or numbness in the hands and feet (carpal tunnel-like symptoms) from fluid shifts

Carnitine metabolism in hypertensive heart failure

Finally, the cladogram (in addition to Supplementary Table S1) clearly illustrated that the unclassified genera fell within multiple orders/families

Given these inconsistencies, future research should focus on well-designed, large-scale RCTs that incorporate biomarker-guided stratification (e.g., SELENOP levels, GPx activity) to identify subgroups that would benefit most from selenium supplementation

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