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(More on that combination in our Matrixyl 3000 vs Retinol guide.) vs

All included patients received acetazolamide, while some received additional therapy with a GLP-1 agonist, either liraglutide or semaglutide

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Rabstein, Peters, and Spahn 1973

The STEP 8 head-to-head data eliminates confounders inherent in cross-trial comparisons and definitively establishes semaglutide's superiority in this population

It is also wise to ask whether the timing of your levothyroxine or natural desiccated thyroid should be reviewed if nausea or reduced appetite make morning routines more difficult