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Biochem Soc Trans 39(4):11021106

Increased Requirements: Rapidly replenishes B vitamin levels during periods of high metabolic demand, such as post-surgery or chronic stress

Chinchilla middle ears challenged with sapA mutants deficient in haem-iron uptake demonstrated a tendency towards a more persistent phenotype, favouring intracellular survival and a dampened cytokine response compared to the parent strain (Raffel et al., 2013)

Autophagy can modulate the expression and activity of apoptosis-related proteins, thereby indirectly altering cellular susceptibility to ferroptosis (38)

Free radicals, like reactive oxygen species (ROS) and reactive nitrogen species (RNS), are naturally occurring, toxic compounds that are formed when the body converts food to energy