In-depth exploration of the regulatory mechanisms of tumor nitrogen metabolism not only helps to reveal the molecular basis of tumor development, but also provides a theoretical basis for the development of new tumor therapeutic strategies
146 RedondoR
(33)] found that intermittent fasting in older mice (14 months old) can enhance the activity of the nicotinamide adenine dinucleotide (NAD+)/Sirt1 antioxidant system, which reduces ROS accumulation, prevents DNA damage and cell apoptosis, increases follicle numbers, and improves oocyte meiotic and embryo development capabilities, thereby significantly delaying reproductive aging
Methods in Enzymology: Academic Press
As pesquisas pr-clnicas evidenciaram um amplo espectro de atividades biolgicas, incluindo a citoproteo gstrica, a modulao da via do xido ntrico (NO) e a interao com o sistema dopaminrgico
Lavoie S, Murray MM, Deppen P, Knyazeva MG, Berk M, Boulat O, et al