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Nevertheless, the consistency of preclinical findings has fueled optimism that GLP-1based therapies may ultimately find uses far beyond diabetes and obesity

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Information about taste acquired in the TBC is finally transmitted to the central nervous system via the so called labeled line principle. This means, that for example, a single sweet-taste cell is connected to a specific sweet-neuron within the geniculate, trigeminal (fungiform taste buds) or petrosal ganglion (circumvallate and filiform papillae) [53]