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This inherent conformational heterogeneity reflected in a cloud-like representation of their conformational ensembles poses a significant obstacle to conventional structural determination techniques, as it prevents the resolution of a unique, high-resolution structure

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17,120 Some variables in utero (in the womb), including maternal smoking during pregnancy, premature birth and/or low birth weight, and/or maternal stress, are seen as risk factors but not causative links to ADHD