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Its important to note that while there are similarities between Phase I and Phase II metabolism, there are also distinct differences in the types of reactions, enzymes involved, and the nature of the metabolites formed
Nausea and diarrhea were common gastrointestinal side effects that occasionally caused people to stop taking the medication
2) Hormonal interactions: oestrogen may synergise with GLP-1 RAs to enhance appetite regulation by activating brain regions involved in controlling food intake and modifying reward pathways [55, 56]
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From a drug delivery perspective, approaches such as ingestible devices, ionic liquids and various technologies to exploit active uptake mechanisms are showing real promise
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