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Am J Physiol 249:R514-521
In animal studies it reduces inflammatory markers and promotes healing across gut, tendon, and other tissues, proposed to work through nitric oxide and angiogenesis pathways
This has been demonstrated with the 5-HT 4 agonist, prucalopride, which modified responses of T2helper cells and shortened post-operative ileus ( Targeting Sensations With D 2 /D 3 and NK 1 Antagonists For upper gastrointestinal disorders associated with increased gastric sensation, such as functional dyspepsia, the dopaminergic D 2 / 3 antagonist, trazpiroben (TAK-506) administered for 1 week significantly increased the volume to fullness during a nutrient drink test, compared to baseline ( 1 receptor antagonist, aprepitant, improved multiple symptoms of gastroparesis including nausea ( 1 receptor antagonist, tradipitant, improved several symptoms of gastroparesis in a 4-weeks, randomized, controlled trial ( Ghrelin Receptor Agonist Ghrelin is predominantly located in the stomach
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GHK-CU benefits compound with consistent use
