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This histone modification has been shown to upregulate key pathways and proteins, including Wnt/-catenin, NF-B, PD-L1, and GDF15, thereby contributing to immune escape and therapeutic resistance in brain tumors (Fig

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Decreased HO-1 expression in PE may result from placental hypoxia or hemolysis, leading to local accumulation of hemoglobin and excessive oxidative stress [29]

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Larger and long-term studies are needed to generate more evidence for Glutathione to be established as a safe & effective skin-whitening agent