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Genomics 1992

Instead, Molinoff PB, et al

Semaglutide may increase your energy expenditure by stimulating the GLP-1 receptors in the brain, which are involved in regulating motor activity and reward pathways

In cell and animal studies, it and its metabolites (e.g., berberrubine, palmatine) boost secretion of GLP-1, increase GLP-1 receptor expression, and limit GLP-1 breakdown

The HGF/c-Met pathway is one of the brain's core growth and repair systems