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Data has shown that treatment with Lactobacilli supernatants or combinations of other probiotics results in lower polymicrobial biofilm thickness and lower matrix density than does treatment with a non-probiotic agent (Song and Lee, 2017
Ohno, Y., Kihara, A., Sano, T
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Petrilli, C
In the context of the Melanotan II pathway, this is relevant because Melanotan II is a melanocortin receptor agonist, and MC1R is one of the receptor-family members that responds to melanocortin-related signaling