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Validation of uromodulin as a candidate gene for human essential hypertension

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, TNF, IL-1, IL-6, iNOS) in stroke models

Sterile injectable drugs account for 71 percent of current shortages, while nearly 44 percent of drugs in shortage rely on at least one key starting material produced exclusively in a single country

The FDA resolved the semaglutide shortage in late 2024 and the tirzepatide shortage in early 2025, narrowing but not closing that lane

By contrast, exenatide and roflumilast were associated with greater uncertainty, with 95% credible intervals crossing the null