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What to look for in a medical cooler Temperature range that matches tirzepatide requirements (36 to 86 degrees Fahrenheit) TSA-approved for air travel Capacity for the number of pens or vials you are bringing Duration of cooling that exceeds your longest expected period without access to a refrigerator A barrier system that prevents direct contact between frozen packs and medication Compact enough to fit in your carry-on or personal item For most travelers, a gel pack insulated cooler in the $30 to $60 range is sufficient