IV glutamine therapy has shown promise in improving cognitive function and mitigating neurodegenerative disorders
Peptide solutions are much less stable than powders
However, the authors of these meta-analyses listed some limitations that open the way for carrying out more RCTs to answer questions: a small number of available trials and high heterogeneity between included studies 107
For statistical analysis we used JASP (version 0.17.1), a software package for Bayesian statistics 46
Glia serve as a major supplier of cysteine for neuronal glutathione synthesis, and 5060% of a glutamate neurotransmitter is derived from the glutamine-glutamate shuttle between neurons and glia, with smaller amounts of glutamate transmitter derived from glycolysis (1214)
2.6 Analysis of cytokines in tears and HCEpiC cell cultures To determine cytokine levels from recovered tears and supernatant from treated HCEpiC cells, the LEGENDplex Human Inflammation Panel 1 (13-plex) flow cytometry-based assay kit was used (BioLegend, San Diego, CA)
