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The Phase 2 trial showed meaningful reductions in systolic blood pressure in participants taking retatrutide

Weight loss may temporarily pause or reverse slightly during post-operative recovery due to reduced activity, inflammation, and medication pause

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As a result, it has more interactions with the central nervous system

Mitochondrial dysfunction further enhances protein misfolding and oxidative stress

This post-surgical gut paralysis renders some patients unable to eat while saddling them with serious constipation, bloating, and discomfort and keeping them in hospital much longer than they otherwise would have been