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10.1002/med.21419 224 PurisE.GyntherM.AuriolaS.HuttunenK

Certain antibiotics may interact with the cyanocobalamin component through effects on vitamin B12 metabolism or efficacy

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Peripheral whole blood was collected in the perioperative setting via a venous catheter immediately before surgery using K 2 -EDTA-coated tubes (BD Biosciences, 367899)

The combination of methylcobalamin and folinic acid induced increases of 15% in total glutathione and 20% in reduced glutathione, respectively ( We then investigated the correlation between behavioral improvements and changes in intracellular glutathione concentrations