Clinical studies suggest collagen supplementation may help: reduce knee osteoarthritis pain improve joint function support tendon rehabilitation when combined with exercise Examples of Osteoarthritis studies: Examples of Tendon studies: Unlike injectable peptides, collagen supplements function as nutritional support, not pharmacologic signaling molecules
application with glutathione peroxidase-1 gene-encoded adenovirus vector
live Akk , pasteurised Akk and Akk s outer protein Amuc_1100 could upregulate aryl hydrocarbon receptor (AhR) targeted genes, including CYP1A1 , IL-10 and IL-22 , suggesting that Akk could activate AhR signaling by regulating tryptophan metabolism, thereby attenuating colonic inflammation [296]
doi: 10.1007/s10792-017-0453-2
Stamler JS and Slivka A (1996)
doi: 10.3892/etm.2020.9504 40 KimTWLeeHG