Methods We investigated the effects of TIR on markers of neuronal growth (CREB and BDNF), apoptosis (BAX/Bcl2 ratio) differentiation (pAkt, MAP2, GAP43, and AGBL4), and insulin resistance (GLUT1, GLUT4, GLUT3 and SORBS1) in a neuroblastoma cell line (SHSY5Y) exposed to normal and high glucose concentration
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Liraglutide was approved in the US for type 2 diabetes in 2010 and for weight loss in 2014
Analyses excluded missing laboratory or anthropometric data
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confirmed that the lower antioxidant enzyme activities might lead to oxidative stress through the oxidation of DNA and protein carbonyl content (general indicator marker of protein oxidation), which may affect the health status of FM patients [32]