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Preclinical studies suggest that GLP-1RAs have a beneficial effect on major NAFLD histological outcomes, i.e., hepatic steatosis and inflammation, through multiple intrahepatic mechanisms, including increased fatty acid -oxidation, activation of autophagy, suppression of inflammation, and oxidative stress

We also confirmed that the association of rs10305420 with GLP1 medication efficacy cannot be accounted for by T2D or smoking status (Supplementary Information and Supplementary Tables 7 and 8)

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