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At the beginning of 2016, results from several clinical trials demonstrated that novel drugs, such as GLP-1RAs and SGLT-2is, showed efficacy in reducing the incidence of cardiovascular events in an unprecedented manner
SA node effect shud be right from beginning, why sympathetic effect on SA shows after a lag at 24 weeks, also if it's as shown in graph peaks after hiatus is this due to drug induced Increased basal metabolic rate(obvioous will be increased HR)
No antidepressant is approved by the FDA for treating cataplexy 10
Mounting research shows GLP-1 agonists warrant a closer look, especially for alcohol addiction
Holecek M
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