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A broader mechanistic review by Seiwerth and colleagues in Current Pharmaceutical Design laid out how BPC-157 seems to borrow the same angiogenic and growth-factor pathways the body uses to heal the gut, and apply them to tendon, ligament, muscle, and bone (Seiwerth et al., 2018)

This elevation in NAD+ levels activates critical metabolic pathways including SIRT1 (sirtuin 1), a longevity-associated protein that regulates insulin sensitivity, mitochondrial function, and cellular stress resistance