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Annual assessment of morning cortisol and ACTH is recommended, with ACTH stimulation testing in cases of abnormal results, to enable early detection and initiations of steroid replacement therapy (94)

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However, lifestyle changes including diet, exercise, and behavior adjustments remain a key strategy, typically leading to 510% weight loss

[DOI] [PubMed] [Google Scholar] 81

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Although its a neurotransmitter (the word neuro leading us to believe its a chemical found in the brain),80-90% of the serotonin in a human body is found in our gut