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These findings highlight the critical role of THC-induced oxidative stress as a contributing factor to cannabinoid-mediated neuropsychiatric risk and identifies a novel antioxidant treatment candidate for the prevention and/or reversal of these pathophysiological outcomes

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Phase 2 (48 weeks, 12mg): 24.2% weight loss

SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2

J Immunol 1985

In a study of elderly subjects, acetyl-L-carnitine treatment reduced physical and mental fatigue, reduced muscle pain, and improved cognitive function [37]