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Bipolar disorder similarly exhibits disruption of the Firmicutes / Bacteroidetes ratio and reduced -diversity, featuring increased Streptococcaceae and Bacteroidaceae abundance contrasting with depletion of anti-inflammatory commensals such as Faecalibacterium ( 249).Among neurodegenerative disorders, Parkinsons disease shows increased abundance of Lactobacillus and Bifidobacterium with concurrent reduction in Faecalibacterium , Coprococcus , and Blautia ( 250, 251), where decreased Blautia abundance correlates with clinical severity and reduced fecal butyrate levels (252)
These include [23][24]: Orange pigmentation of the skin Lowered blood sugar levels Lowered blood pressure Inhibition of 5-alpha-reductase, thereby inhibiting the conversion of testosterone to dihydrotestosterone (DHT) Due to its potential immune-enhancing activity, astaxanthin should be used cautiously in those autoimmune disorders or people taking immunosuppressants
