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In vivo PK studies in mice revealed favourable concentrations of MF-01 to treat infections in the gastrointestinal tract with ~1.5-fold higher concentrations of MF-01 in plasma and urine compared with Metro-P3 (Fig

(2004) Gastroenterology n=28 Study demonstrating ipamorelin accelerated recovery of gut motility and feeding tolerance post-operatively

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Within the hypothalamus, GLP-1 receptors are concentrated in the arcuate nucleus and paraventricular nucleusregions that integrate peripheral metabolic signals and coordinate feeding behaviour