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Additionally, mRNA expression of iron response element binding protein 2, encodes a master regulator of iron metabolism), and CS (citrate synthase, regulating the mitochondrial fatty acid metabolism) was upregulated in both models, while ACSF2 ((acyl-CoA synthetase family member 2, regulating the mitochondrial fatty acid metabolism) was upregulated only in APPswe/PS1dE9 mice

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doi:10.1038/s41467-025-58680-y

GABAergic Modulation Without Sedation Selank's most studied mechanism is allosteric modulation of the GABAergic system the primary inhibitory network in the central nervous system

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