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The 0.9% benzyl alcohol preservative inhibits microbial growth in the vial after multiple punctures, allowing the same vial to be used across multiple reconstitution events within standard stability windows
A thicker needle is necessary for IM injections to penetrate the muscle tissue effectively
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J Korean Med Sci
Furthermore, in bile ductcannulated (BDC) rats, the average recovery rates of total radioactivity in bile, urine, feces, and cage cleaning fluid collected during 72 h after dosing were 9.08% 0.86%, 17.77% 6.35%, 2.73% 0.40%, and 0.91% 0.13%, respectively (Table 8