NAD+ therapy is relatively new, and while there are promising animal studies and early human reports, its still an area of active research
Like all weapons, it has dark sides
In 537 adults with type 2 diabetes (85% treatment-naive, on stable metformin), the 12mg dose produced HbA1c reductions up to 2.0% and weight loss up to 16.8% at 40 weeks, with no plateau observed
Additionally, the safety and efficacy of pentagastrin as an adjunct to medical imaging techniques, such as gastric scintigraphy, will be examined
These are not intended to achieve full therapeutic effect as standard doses, but to get slow and gradual results
Because the mechanism of action of SGLT-2 inhibitors is dependent on kidney function, these agents are not recommended for patients with diminished renal function