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It represents a new class of triple-agonist metabolic therapy with the potential to redefine fat loss, body recomposition, and metabolic health

In contrast, APOE4 has been consistently linked to increased risk and earlier onset of Alzheimers disease (AD), possibly due to its detrimental influence on lipid homeostasis, mitochondrial integrity, and neuroinflammatory pathways (Volgman et al., 2024

Additionally, higher levels of total cholesterol, LDL, triglycerides, and lower HDL were observed in the responsive group, suggesting greater insulin resistance [15]

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