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Physically, we notice wrinkles because we are creating less collagen as our cellular turnover slows down
One explanation for this may be that as long as the intake of protein is sufficient, serum IGF-I levels will remain relatively stable (115), i.e., the intake of calories per se does not alter serum IGF-I levels
The STEP 2 trial, published in The Lancet, investigated the effect of a standard 1.0 mg dose of semaglutide vs