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When administering a higher dose, the benefits should be weighed against the risks

However, if autophagy is impaired in the pancreatic acinar cells, it may not be able to take care of the intracellular damage leading to the inflammatory cascade.[ref] Additionally, autophagy is important in tamping down inflammation due to tissue damage

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Anti-VEGF injections vs angiogenic peptides Anti-VEGF mechanism: Bevacizumab (Avastin), ranibizumab (Lucentis), aflibercept (Eylea) bind VEGF preventing receptor binding