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Supplementary information The spectrophotometer is set at a 412-nm wavelength and a continuous reading is performed for a few minutes until a plateau is reached

Simply apply a few drops to clean, dry skin, gently massaging it in, and follow up with your favorite moisturizer for optimal results

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Repeated measurements of endocrine markers were analyzed with linear mixed-effects (LME) models, having drug condition (placebo, oral cannabis, smoked cannabis, and vaporized cannabis), session number (1, 2, 3, and 4), blood sampling time-point (T1, T2, T3, and T4), and drug time-point interaction as fixed effects, individual subjects as a random effect (random intercept and slope), and each hormone as the outcome

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The long-term effects on the body are unknown